Summary: Your e-mail list is your biggest opportunity to gain prospects and turn them into smokin’ hot leads. It gets the best ROI out of any digital marketing channel – by far. Are you doing it? Learn why you should and how to get the most out of it. Where’s the best ROI in online B2B lead generation? Where should you spend lots of your time? No need to get complex. Think simple. And absolutely, positively, unequivocally, (say that 3 times fast out loud) no other channel even comes close.